The human brain, as depicted by a network of interconnected regions, acquires a distinctive structural and functional architecture over the course of development. It is postulated that this distinctive architecture of the brain provides a basis for the emergent functional systems and thereby, of behavioral capacities. Therefore, studying developmental changes in the organization of the brain network is critical for understanding neurobiological substrates of cognition, learning, and mental conditions. This becomes especially important during infancy and adolescence when the human brain undergoes a protracted course of remodeling to support the rapid expansion of its behavioral repertoire.
We develop novel brain connectivity analysis methodologies that enable exploration of the links between the brain network and behavioral outcomes in development, diseases, and disorders.
Brain-Behavior Links in Normative and Clinical Samples
Elaborating links between the brain network and behavior is critical for better understanding normative development as well as deviations from this normative pattern in clinical samples. We develop methods to computationally characterize links between the brain and behavior....
Neurobiology of Autism Spectrum Disorder
Increasing evidence suggests that autism spectrum disorder (ASD) originates from neurodevelopmental abnormalities, highlighting a need for new research strategies that combine neuroimaging, genetics, and behavioral assessment. Our research on the development of new methodologies that blend ...
Novel Methods for Brain Connectivity Analysis
Understanding the organization of brain networks necessitates development of sophisticated statistical tools that harness power of network analysis and machine learning. We develop novel computational neuroimaging methods to better characterize brain connectivity....